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- W2352506579 abstract "Objective:To verify the curative effects and safety of cyclosporin A(CsA)treating lupoid nephritis(LN)and to find a therapy to prevent remission when dosage of CsA deduced or when CsA was no longer given.Methods:Patients in the control group were treated with sudden dose onset of Cyclophophamide (CTX).Subjects in the treatment group were given CTX when CsA was deduced,and CsA was stopped when CTX’s curative effects were observed.Results:Our data showed that CsA and CTX have almost the same effect,but CsA had more rapid effects on decrease of erythrocyte sedimentation rate,urine protein,and titer of anti-ds DNA and increases of serium albumin and complement 3 than those of CTX.No recurrence has been observed in the CsA treated group,for 1 year follow-up survey.Conclusion:Our observation showed that CsA is effective in treating LN and can deduce the dosage of bormones and CTX,which have side effects.And more importantly,CTX addition during CsA gradual deduction can prevent recurrence of the disease following the termingation of CsA.Hepatorenal toxicity was rarely seen when it was administered in small dosage and for short term.For severe LN,CsA,that CTX intead of CsA maintenance therapy was given when clinic remission was acquired was an effective remedy.The therepic procedure is worthy of further investigation." @default.
- W2352506579 created "2016-06-24" @default.
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- W2352506579 date "2001-01-01" @default.
- W2352506579 modified "2023-09-26" @default.
- W2352506579 title "Comparison of Curative Effects of Cyclosporin A and Cyclophophamide on Treating Lupoid Nephritis" @default.
- W2352506579 hasPublicationYear "2001" @default.
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