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- W2352506720 abstract "Objective:To investigate the protective effects and mechanism of ligustrazine on myocardial ischemia reperfusion injury(MIRI) in rats.Methods:30 Wistar rats were divided into three groups randomly:sham operation group,ischemia reperfusion injury group(IR),and ligustrazine preconditioning group(LI).The model of MIRI was produced,Immunohistochemical S-P method was used to detect the expressions of HSP25 and p38MAPK proteins in MIRI tissues.Results:Compared with IR group,the expression of HSP25 protein in LI group increased significantly(P0.01),the expression of p38 mitogen activated protein kinase(MAPK) protein decreased significantly(P0.01).Conclusion:Ligustrazine can enchance the expression of HSP25 and reduce systemic inflammatory response and protect myocardial ischemia reperfusion injury." @default.
- W2352506720 created "2016-06-24" @default.
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- W2352506720 date "2008-01-01" @default.
- W2352506720 modified "2023-09-23" @default.
- W2352506720 title "Effects of ligustrazine on expression of HSP25 and p38MAPK proteins in rats with myocardial ischemia reperfusion injury" @default.
- W2352506720 hasPublicationYear "2008" @default.
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