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- W2352568758 abstract "OBJECTIVE Take the HL60(Human promyelocytic leukemia cell line) and B16BL6(mouse melanoma cell line) as the object,and the inhibition ratio and the apoptosis of the cells as the indicatrix,the purpose was estimate the effect of the extraction and the polysaccharide of Oldenlandia diffusa.METHODS Aqueous extract,alcohol extract and polysaccharide were applied to the B16BL6 and HL60.Then the cells inhibition ratio was detected by MTT method and the apoptosis of cells by FCM(flow cytometry) method.RESULTS (1) In MTT quantitate detection,the extractives of Oldenlandia diffusa had the inhibitive function to tumors propertional to the concentration.(2) The alcohol extract and polysaccharide of Oldenlandia diffusa have the effect of the apoptosis and the cell cycle of B16BL6 by FCM method.CONCLUSION The aqueous extract,alcohol extract and polysaccharide of Oldenlandia diffusa have the remarkable inhibitive function to the HL60 and B16BL6.The alcohol extract and polysaccharide have the remarkable function to induced the apoptosis of the cells." @default.
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- W2352568758 date "2009-01-01" @default.
- W2352568758 modified "2023-09-25" @default.
- W2352568758 title "Study on the Anti-tumor effect of Oldenlandia diffusa on HL60 and B16BL6 cell line in vitro" @default.
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