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- W2352582023 abstract "Objective:To investigate the effect of cytokines on the Graves ophthalmopathy (GO). Methods: The level of TNF-α, IL-4 and thyroid hormone were determined in 45 patients with Graves disease (GD) but without phthalmopathy, 36 patients with Graves ophthalmopathy and 36 control subjects. Results: The levels of TNF-α and IL-4 in GD and GO group were significantly higher than that in control group. TNF-α/IL-4 ratio showed no significant difference between the GO group and control group. Conclusion: The patients with GD mainly display an increase of IL-4, indicating that the Th2-mediated humoral immunity plays a predominant role in patients with GD but without ophthalmopathy. A Th0-type immune response may be presented in patients with GO, and both cellular and immune response play a role in the development of GO." @default.
- W2352582023 created "2016-06-24" @default.
- W2352582023 creator A5078433982 @default.
- W2352582023 date "2008-01-01" @default.
- W2352582023 modified "2023-09-24" @default.
- W2352582023 title "Expressions of serum IL-4 and TNF-α in patients with Graves ophthalmopathy" @default.
- W2352582023 hasPublicationYear "2008" @default.
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