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- W2352615317 abstract "OBJECTIVE To investigate the distribution and drug resistance of the pathogenic bacteria causing the lower respiratory tract infections in the ICU so as to analyze the risk factors of multi-drug resistance and guide the reasonable treatment.METHODS The sputum specimens were collected from the patients with the lower respiratory tract infections who were treated in the ICU from Jan 2010 to Oct 2012.The routine bacterial culture and identification were performed,the species of the pathogens and the drug resistance were analyzed;the patients with the multidrug-resistant bacteria infections were assigned as the observation group,and the patients with the non-multidrug-resistant bacteria infections were set as the control group,the clinical data of the two groups of patients were collected and analyzed,and the risk factors were analyzed.RESULTS Totally 262 strains of pathogens were isolated from the sputum specimens of the 204 patients;there were 138(52.7%) strains of gram-negative bacilli,among which the detection rate of Pseudomonas aeruginosa was the highest(23.7%);there were 84(32.0%) strains of gram-positive cocci,among which the detection rate of Staphylococcus aureus was the highest(22.1%);there were 40(15.3%) strains of fungi,among which Candida albicans accounted for 8.4%;the muldirug-resistant P.aeruginosa,S.aureus,and A.baumannii were the predominant species;the multivariate logistic regression analysis indicated that the more than 70 years of age,mechanical ventilation duration more than 2 weeks,use of carbapenem antibiotics,COPD history,and diabetes history were the independent risk factors of the multidrug-resistant bacteria infections.CONCLUSION The complications of COPD or diabetes,mechanical ventilation duration more than 2 weeks,and long term use of third generation cephalosporins or carbapenem antibiotics are the risk factors associated with the lower respiratory tract infections in the ICU patients.It is necessary to detect the pathogens and drug resistance and use the susceptible antibiotics for the treatment." @default.
- W2352615317 created "2016-06-24" @default.
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- W2352615317 date "2013-01-01" @default.
- W2352615317 modified "2023-09-23" @default.
- W2352615317 title "Pathogens causing lower respiratory tract infections in ICU and risk factors of multi-drug resistance" @default.
- W2352615317 hasPublicationYear "2013" @default.
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