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- W2352650672 abstract "Objective To observe the changes of human neutrophil peptide(HNP) 1-3 content in plasma quantitatively during perioperation of cardiac surgery under cardiopulmonary bypass(CPB),and to explore the role of changes of HNP1-3 content in early diagnosis of system inflammatory response syndrome(SIRS) after CPB.Methods The contents of HNP1-3 in plasma during perioperation of 21 cardiac surgeries under CPB were measured quantitatively using ELISA method,and the contents of CK,CK-MB and C-RP in plasma were measured at the same time points as that of HNP1-3.Results The contents of HNP1-3 in plasma were(54.55±26.45)ng/ml before CPB,and they were(435.45±500.13)ng/ml 0.5h after CPB which were significantly higher than that before CPB(P0.01).The contents of HNP1-3 rose to peak value 4 hours after CPB,which were(454.18±(651.20))ng/ml,and then the contents of HNP1-3 decreased.The peak times of CK,CK-MB and C-RP in plasma were 24 hours after CPB,and the peak values of them were(1587.46±1500.56)U/L,(38.18±39.27)U/L and(62.63± 27.08)mg/L respectively.Conclusion The response of HNP1-3 to the SIRS after CPB is sensitive and rapid,and the changes of content of HNP1-3 in plasma might be used to predict the serious degree and tendency of SIRS after CPB." @default.
- W2352650672 created "2016-06-24" @default.
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- W2352650672 date "2006-01-01" @default.
- W2352650672 modified "2023-09-25" @default.
- W2352650672 title "The changes of HNP1-3 content in plasma during perioperation of cardiac surgery under cardiopulmonary bypass" @default.
- W2352650672 hasPublicationYear "2006" @default.
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