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- W2352672316 abstract "Eleven avirulent Newcastle disease viruses(NDVs) were isolated from ducks in China from 2002 to 2007.Phosphoprotein(P) genes of these NDVs were amplified by RT-PCR and sequenced.The P gene sequences were analyzed using bioinformatic software(SNAP and CODEML) to examine genetic variability and their effect on virus evolution.The P gene sequences of twenty eight NDV reference strains in GenBank were also included for comparison in the present study.Phylogenetic analysis of the P gene indicated that Class I genotype 2 Chinese viruses were closely related to some European and American viruses and Class I genotype 3b viruses formed a separate branch,which geographically distributed within China only.Class II genotype Ib viruses diverged from the representative strains of genotype I and the vaccine virus Queensland V4,the latter is extensively used in China.The bioinformatic analysis revealed graphic patterns of the dS and dN values and confirmed the prevalence of positive selection at terminal regions of P proteins(aa 62-113 and 137-198).Class I genotype 3b virus was unique to China.The P protein of different genotypes was most highly variable and the variability was presented in a few localized regions under negative and positive selections." @default.
- W2352672316 created "2016-06-24" @default.
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- W2352672316 date "2009-01-01" @default.
- W2352672316 modified "2023-09-25" @default.
- W2352672316 title "GENETIC VARIATION OF PHOSPHOPROTEIN GENE OF AVIRULENT NEWCASTLE DISEASE VIRUS OF DUCK ORIGIN IN CHINA" @default.
- W2352672316 hasPublicationYear "2009" @default.
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