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- W2352688786 abstract "Objective To study the influence of 89 SrCl_2 on the immunological functions in the patients with bone metastases. Methods Forty-two patients with proved bone metastases were treated with 89 SrCl_2 and according to the final therapeutic efficiency for the metastatic lesions,the patients were divided into efficacious and inefficacious group. Twenty untreated healthy adults served as control group. The T lymphocyte subsets CD +_4,CD +_8,CD +_4/CD +_8 were analyzed before and after 89 SrCl_2 treatment. Results The immunological indexes were not significantly different between the two patient groups before the therapy of 89 SrCl_2. The indexes between the controls and patients before and after the therapy were different significantly (P0.05). The indexes of inefficacious patients differed from that of the efficacious patients too (P0.05). After being treated with 89 SrCl_2,37 (88.10%) patients' immunological functions were improved,33 patients (78.57%) stated that their pain were effectively relieved,29 (69.05%) patients' bone metastatic lesions reduced. Conclusions The immunological functions in the patients with bone metastases were inhibited obviously. Treating with 89 SrCl_2 can improve their immunological functions to a certain extent. The recovery level of the inefficacious patients was lower than that of the efficacious patients. The changes of immunological functions can reflect the therapeutical effectiveness." @default.
- W2352688786 created "2016-06-24" @default.
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- W2352688786 date "2004-01-01" @default.
- W2352688786 modified "2023-09-26" @default.
- W2352688786 title "The changes of the immunological indexes in the patients with bone metastases treated with ~(89)SrCl_2" @default.
- W2352688786 hasPublicationYear "2004" @default.
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