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- W2352707230 abstract "OBJECTIVE:To estabilish a HPLC-MS method for determining enalapril in human plasma METHODS:Alprozalam was added into plasma sample as an internal standard,then supernate of the sample was extracted through solid-phase extration column,washed with methanol and detected by HPLC-MS method:column,ODS C18;mobile phase,methanol-0 01% formic acid(45∶55);flow rate,0 8ml/min;capillary voltage,3 81kV;cone voltage,39 0V The selected ion was determined by EST RESULTS:The calibration curve was linear within the range of 2 5～400ng/ml r=0 9 996,the recovery was 102 2%,RSDs of intra -day and inter-day were 4 0% and 5 4%,respectively CONCLUSION:The method is accurate and sensitive with no endogenous interference It can be applied to studying the pharmacokinetics and bioavailability of enalapril tablets in humans" @default.
- W2352707230 created "2016-06-24" @default.
- W2352707230 creator A5064832836 @default.
- W2352707230 date "2002-01-01" @default.
- W2352707230 modified "2023-09-25" @default.
- W2352707230 title "Determination of Enalapril in Human Plasma With HPLC-MS" @default.
- W2352707230 hasPublicationYear "2002" @default.
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