Matches in SemOpenAlex for { <https://semopenalex.org/work/W2352716076> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2352716076 endingPage "9" @default.
- W2352716076 startingPage "346" @default.
- W2352716076 abstract "To investigate the expression of matrix metalloproteinases-9 (MMP-9) and tissue inhibitor of metalloproteinases-1 (TIMP-1) mRNA in the endometrium during mid-luteal phase in women with unexplained infertility and its steroidal regulation.In situ hybridization method was utilized to detect the location of MMP-9 and TIMP-1 mRNA. Reverse transcription polymerase chain reaction (RT-PCR) method was utilized to detect and quantitate MMP-9 and TIMP-1 mRNA expression levels in the endometrium during mid-luteal phase. Serum concentration of estradiol (E(2)) and progesterone (P) were measured by radioimmunoassay. Thirty-eight patients with unexplained infertility were included as study group, and 20 women with male factor infertility or normal volunteers were selected as control group.MMP-9 and TIMP-1 mRNA were diffusely distributed in the cytoplasm and nuclei of glandular and stromal cells. Their staining in control group were more abundant than those in study group. Endometrial MMP-9 and TIMP-1 mRNA expression during mid-luteal phase showed by RT-PCR in the study group were significantly lower than those in the control group (0.42 +/- 0.19 Vs 0.57 +/- 0.19, P < 0.05; 0.59 +/- 0.19 Vs 0.81 +/- 0.20, P < 0.01 respectively). Serum P of the study group was significantly lower than that of control group [(34 +/- 15) nmol/L Vs (53 +/- 17) nmol/L, P < 0.01]. Serum P level was positively correlated with MMP-9 mRNA only in control groups.MMP-9 and TIMP-1 mRNA might play an important role in the process of implantation. The decreased expression of their gene related to P level might be one of the major causes in unexplained infertility." @default.
- W2352716076 created "2016-06-24" @default.
- W2352716076 creator A5029868814 @default.
- W2352716076 creator A5075162983 @default.
- W2352716076 date "2003-06-01" @default.
- W2352716076 modified "2023-10-16" @default.
- W2352716076 title "[Expression of matrix metalloproteinases-9 and tissue inhibitor of metalloproteinases-1 mRNA in the endometrium during mid- luteal phase in women with unexplained infertility]." @default.
- W2352716076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12895377" @default.
- W2352716076 hasPublicationYear "2003" @default.
- W2352716076 type Work @default.
- W2352716076 sameAs 2352716076 @default.
- W2352716076 citedByCount "0" @default.
- W2352716076 crossrefType "journal-article" @default.
- W2352716076 hasAuthorship W2352716076A5029868814 @default.
- W2352716076 hasAuthorship W2352716076A5075162983 @default.
- W2352716076 hasConcept C104317684 @default.
- W2352716076 hasConcept C105580179 @default.
- W2352716076 hasConcept C109523444 @default.
- W2352716076 hasConcept C126322002 @default.
- W2352716076 hasConcept C134018914 @default.
- W2352716076 hasConcept C143228043 @default.
- W2352716076 hasConcept C16685009 @default.
- W2352716076 hasConcept C187785154 @default.
- W2352716076 hasConcept C2777688143 @default.
- W2352716076 hasConcept C2778580812 @default.
- W2352716076 hasConcept C2779234561 @default.
- W2352716076 hasConcept C2779742232 @default.
- W2352716076 hasConcept C4692481 @default.
- W2352716076 hasConcept C54355233 @default.
- W2352716076 hasConcept C55493867 @default.
- W2352716076 hasConcept C71924100 @default.
- W2352716076 hasConcept C86803240 @default.
- W2352716076 hasConceptScore W2352716076C104317684 @default.
- W2352716076 hasConceptScore W2352716076C105580179 @default.
- W2352716076 hasConceptScore W2352716076C109523444 @default.
- W2352716076 hasConceptScore W2352716076C126322002 @default.
- W2352716076 hasConceptScore W2352716076C134018914 @default.
- W2352716076 hasConceptScore W2352716076C143228043 @default.
- W2352716076 hasConceptScore W2352716076C16685009 @default.
- W2352716076 hasConceptScore W2352716076C187785154 @default.
- W2352716076 hasConceptScore W2352716076C2777688143 @default.
- W2352716076 hasConceptScore W2352716076C2778580812 @default.
- W2352716076 hasConceptScore W2352716076C2779234561 @default.
- W2352716076 hasConceptScore W2352716076C2779742232 @default.
- W2352716076 hasConceptScore W2352716076C4692481 @default.
- W2352716076 hasConceptScore W2352716076C54355233 @default.
- W2352716076 hasConceptScore W2352716076C55493867 @default.
- W2352716076 hasConceptScore W2352716076C71924100 @default.
- W2352716076 hasConceptScore W2352716076C86803240 @default.
- W2352716076 hasIssue "6" @default.
- W2352716076 hasLocation W23527160761 @default.
- W2352716076 hasOpenAccess W2352716076 @default.
- W2352716076 hasPrimaryLocation W23527160761 @default.
- W2352716076 hasRelatedWork W1546099944 @default.
- W2352716076 hasRelatedWork W1594739854 @default.
- W2352716076 hasRelatedWork W2010033349 @default.
- W2352716076 hasRelatedWork W2104198153 @default.
- W2352716076 hasRelatedWork W2352716076 @default.
- W2352716076 hasRelatedWork W2353681240 @default.
- W2352716076 hasRelatedWork W2354203283 @default.
- W2352716076 hasRelatedWork W2374580932 @default.
- W2352716076 hasRelatedWork W2393359706 @default.
- W2352716076 hasRelatedWork W2393736693 @default.
- W2352716076 hasVolume "38" @default.
- W2352716076 isParatext "false" @default.
- W2352716076 isRetracted "false" @default.
- W2352716076 magId "2352716076" @default.
- W2352716076 workType "article" @default.