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- W2352803110 abstract "Simian virus 40 chromatin was incubated after purification by sucrose density-gradient centrifugation with var- ious circular double-stranded DNA substrates. Monomeric rings were converted in the presence of Mg2+ to structures possessing a higher degree of complexity. Dimeric catenanes, as well as mul- timeric linear structures and concatemers, were generated, in- dicating that recombination events had occurred in vitro involving covalent linkage between different DNA molecules. Further- more, apparently fused dimeric rings were observed. Their struc- tures suggest that they may be recombination intermediates such as those described in a prokaryotic system (Potter, H. & Dressler, D. (1976) Proc. Natl. Acad. Sci. USA 73, 3000-3004). Recombi- nation did not take place between heterologous DNA substrates, as exclusively homologous multimeric DNA structures were observed." @default.
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- W2352803110 date "2016-01-01" @default.
- W2352803110 modified "2023-09-27" @default.
- W2352803110 title "IA structures mediated by" @default.
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- W2352803110 hasPublicationYear "2016" @default.
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