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- W2352804670 abstract "Objective Investigate the roles of eotaxin(chemotactic factor of eosinophils)in pathogenesis of eosinophilic airway inflammation and the differences between ashma and eosinophilic brochitis.Methods 45 patients in stable phase with asthma(A group,13 cases),eosinophilic bronchitis(EB group,11 cases),chronic bronchitis(CB group,12 cases) and and 9 healthy volunteers as controls(C group)had participated in sputum induction.The concentration of eotaxin in supernatant was measured by sandwich enzyme linked immunosorbent assay(ELISA).Results The differences of the eosinophil(Eos)/leukocyte(Leu)% and the concentration of eotaxin in A group[(19.2±9.7)%;(0.251±0.118)g/L],EB group[(11.4±6.1)%;(0.146±0.079)g/L]between in CB group[(0.9±0.6) %;(0.043±0.036)g/L],C group[(0.8±0.4)%;(0.031±0.013)g/L]are significant(P0.05).The differences of those in A group between in EB group are significant too(P0.05).Conclusion Eotaxin possiblely particulates in eosinophilic airway inflammation in patients with ashma and eosinophilic bronchitis by selective chemotactic activity on eosinophil,but it possiblely reachs to higher level in ashma than in eosinophilic bronchitis." @default.
- W2352804670 created "2016-06-24" @default.
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- W2352804670 date "2011-01-01" @default.
- W2352804670 modified "2023-09-24" @default.
- W2352804670 title "Eotaxin in induced sputum in patients with asthma and eosinophilic bronchitis:relationship with airway inflammation" @default.
- W2352804670 hasPublicationYear "2011" @default.
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