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- W2352806681 abstract "Objective To discuss the value of high-resolution MRI in the quantification of osteoporosis. Methods 110 cases were in the study including 52 males and 58 females. According to the bone density, all patients were divided into 4 groups: normal female, abnormal female, normal male and abnormal male. All scans were on left calcaneus with gradient echo sequences on a 1.5 T MRI. Slice thickness was 0.73 mm and spatial resolution was 312 μm×312 μm×730 μm. T2 value were achieved in 50 cases. 5 ROI were selected on the largest sagittal image of calcaneus for analysis. Based on binary images, 29 structure parameters, 1 biodynamic parameter and T2 value were analyzed. The results were also analyzed with statistical methods. Results In normal-abnormal females, normal and abnormal males, 85% of parameters were significant difference. Structural parameters from 97% of up-front calcaneus ROI, 97% of up-post calcaneus ROI and 91% of sub-front ROI were related with bone density. Within statistically available parameters, 77% were from 8-10 points. Parameters for trabecula connectivity like mean framework length、mean trabecula perimeter and euler number have positive correlation with bone density with r=0.729、0.709、0.764,P0.001. euler number has negative correlation with bone density with r=-0.753, P0.001. As biodynamic parameter, anti-stress factor was 6.476～7.694 in normal groups and 2.321～3.036 in abnormal groups with P0.001.anti-stress factor has an obvious positive correlation with bone density. The anti-stress factor of up-post calcaneus has correlation factor from 0.756～0.803 with femoral neck, greater tuberosity, inter tuberosity and pelvis(P0.001). The mean T2 value were 94.72～113.75 ms(P0.001) in normal group and 119.4～127.4 ms (P0.05) in abnormal group. T2 value has positive correlation with age and negative correlation with bone mineral density. Conclusions High-resolution MRI is a valuable method for the quantification of bone trabecula and can provide additional information of osteoporosis. The potential value of bone texture was obvious." @default.
- W2352806681 created "2016-06-24" @default.
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- W2352806681 date "2007-01-01" @default.
- W2352806681 modified "2023-09-27" @default.
- W2352806681 title "The quantification of calcaneus micro-structure with high-resolution MRI" @default.
- W2352806681 hasPublicationYear "2007" @default.
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