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- W2352806909 abstract "Objective To evaluate the effects of buprenorphine with 0.125% bupivacaine for epidural analgesia on the quality of postoperative pain relief in patients underwent transurethral resection of the prostate.Methods Eighty male patients,ASA II-III,scheduled for selective TURP were studied.Combined spinal-epidural anesthesia was performed at L_(2-3) interspace.Postoperative epidural analgesia was started at the end of surgery using a continuous epidural infusion of analgesic solution of buprenorphine with bupivacaine at the rate of 2ml/h.Patients were randomly allocated to receiving 0.125% bupivacaine alone(group A,n=20),buprenorphine 2μg/ml with 0.125%bupivacaine(group B,n=20),buprenorphine 4μg/ml with 0.125%bupivacaine(group C,n=20),or buprenorphine 6μg/ml with 0.125%bupivacaine(group D,n=20).The degree of pain was evaluated by VAS at 1,2,3,8,12,24 and 48h after surgery.The frequency of bladder spasm,the degree of motor block and side effects were also recorded.Results VAS from 3h after surgery was significantly lower in group B,C and D than that in group A(P0.05).Four patients of group A and one patient of group B had bladder spasm within 48 hours after operation.One patient appeared hypersomnia and another one had vomiting in group C.Four patients had nausea and one appeared hypersomnia in group D.Conclusion Adding 2μg/ml or 4μg/ml buprenorphine to 0.125% bupivacaine analgesic solution for epidural analgesia can provide an effective pain relief with less significant side effects." @default.
- W2352806909 created "2016-06-24" @default.
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- W2352806909 date "2006-01-01" @default.
- W2352806909 modified "2023-09-28" @default.
- W2352806909 title "The effect of buprenorphine combined with bupivacaine for epidural analgesia in patients underwent transurethral resection of the prostate(TURP)" @default.
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