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- W2352809718 abstract "OBJECTIVE To explore the relationship between IFN gamma produced by natural killers cells(NK cells) and the pathogenesis of chronic hepatitis B(CHB).METHODS Various samples including peripheral blood mononuclear cells(PBMCs) with chronic hepatitis B were examined for IFN gamma produced by NK cells.The levels of IFN gamma were detected by intracellular cytokine staining.RESULTS The levels of IFN gamma produced by NK cells were significantly higher in the patients with active chronic hepatitis B(4.08±2.75)% than those in the patients with non-active chronic hepatitis B(2.37±1.1 3)% and normal groups(1.27±0.39)%.The levels of IFN gamma produced by NK cells were lower in recovery phase(2.24±1.47)% than in active phase(4.89±2.66)%.CONCLUSION The pathogenesis of chronic hepatitis B may positively relate to the high expression of IFN gamma produced by natural killers cells(NK cells)." @default.
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- W2352809718 date "2011-01-01" @default.
- W2352809718 modified "2023-09-28" @default.
- W2352809718 title "Relationship between expression of IFNγ produced by natural killer cells and condition of patients with chronic hepatitis B virus infection" @default.
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