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- W2352812473 abstract "Objective To investigate the levels of inflammation in type 2-diabetes patients and their relationship with the quality of blood glucose control.Methods A total of 160 type 2-diabetes patients were enrolled,included 84 males and 76 females,who were aged 42-73 years old with a mean age of 63.50.Accorded to the levels of glycosylated hemoglobin(HbAlc),the patients were divided into 2 groups: well-controlled group(n = 92) and poorly-controlled group(n = 68).One hundred healthy individuals were taken as control group(55 males and 45 females,aged 45-75 years old with a mean age of 62.80).The serum concentrations of interleukin-6(IL-6),tumor necrosis factor-alph a(TNF-α),interleukin-1β(IL-1β) and interleukin-8(IL-8) in all participants were measured simultaneously by multiplexed Luminex assay.Results There was significant difference in serum levels of IL-6,TNF-α and IL-8 between the patient and control group(all P 0.01).Moreover,the levels of IL-6,TNF-α and IL-8 of well-controlled group were higher than that of poorly-controlled group(P 0.01).There was no significant difference in levels of IL-1β between patients and controls.Conclusion It is demonstrated that the cytokine of patients with type 2-diabetes is in a state of low-level inflammation.The change in the serum levels of IL-6,TNF-α and IL-8 is closely associated with the quality of glucose control." @default.
- W2352812473 created "2016-06-24" @default.
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- W2352812473 date "2013-01-01" @default.
- W2352812473 modified "2023-09-22" @default.
- W2352812473 title "Effect of glycose control in type 2-diabetes patients on inflammatory factors" @default.
- W2352812473 hasPublicationYear "2013" @default.
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