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- W2352817811 abstract "Stigmatella aurantiaca fruiting body development depends on cell-cell interactions. One type of the signaling molecule stigmolone isolated from S. aurantiaca cells acts to help cells to stay together in the aggregation phase. Another gene product involved in intercellular signaling in S. aurantiaca is the csgA homolog of Myxococcus xanthus. In close relative M. xanthus C signal the product of the csgA gene is required for rippling, aggregation and sporulation. Isolation of homologous gene in S. aurantiaca implicates a probable role of CsgA in intercellular communication. Inactivation of the gene by insertion mutagenesis caused alterations in S. aurantiaca fruiting. The motility behavior of the cells during development was changed as well as their ability to stay more closely together in the early stages of development. Inactivation of the csgA gene completely abolished rippling of the cells. This indicates the crucial role of the CsgA protein in regulating this rhythmic behavior." @default.
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- W2352817811 date "2015-01-01" @default.
- W2352817811 modified "2023-09-26" @default.
- W2352817811 title "Inactivation of Stigmatella aurantiaca CsgA gene impares rippling formation" @default.
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- W2352817811 doi "https://doi.org/10.2298/gensr1501119m" @default.
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