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- W2352864956 abstract "Objective:To study the protective effect of 1,8 dihydroxy 3,5 dimethoxyxanthone(Xan) against the cerebral ischemia reperfusion injury in rat. Methods: 50mg/kg and 10mg/kg of Xan were administered intravenously in rats respectively for ten days.The bilateral common carotid arteries of rats were ligated for 30 min followed by 45 min of reperfusion.The cerebrum was romoved and the contents of water,malondialdehyde (MDA),Ca 2+ and the lactate dehydrogenase (LDH) activity of the brain were determined. Results: Xan(50mg/kg,iv) reduced the contents of water for 6.36%,MDA for 22.12% and Ca 2+ for 20.10%,and increased the LDH activity for 12.44% in the rat cerebrum after cerebral ischemia reperfusion. Conclusion:Xan has protective effect against cerebral ischemia reperfusion damage in rat." @default.
- W2352864956 created "2016-06-24" @default.
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- W2352864956 date "2001-01-01" @default.
- W2352864956 modified "2023-09-25" @default.
- W2352864956 title "Study on the Protective Effect of Xanthone on Cerebral Ischemia reperfusion Damage in Rat" @default.
- W2352864956 hasPublicationYear "2001" @default.
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