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- W2352878682 abstract "Objective To evaluate the efficacy and feasibility of the coil-and-glue method for the reduction of lung volume in rabbit emphysema model.Methods Sixteen rabbits of emphysema model were divided into the occlusion group(n=10),in which both anterior bronchi were occluded using the coil-and- glue method,and the control group(n=6).The maximal static pressure of airway(P_(max)),peak expiratory flow(PEF),end-expiratory volume(EEV)and pressure of oxygen(PO_2)were measured at ante- emphysema,post-emphysema,1 week and 4 week after occlusion respectively.The expectoration(or migration)of coil and collapse of lung were also investigated.Results P_(max)was(20.0±1.3)and(17.1± 1.4)cm H_2O(1 cm H_2O=0.098 kPa)in the occlusion group at ante-emphysema and post-emphysema respectively.P_(max)was(19.2±1.4)cm H_2O in the occlusion group in the 1 week after the occlusion,while (17.1±1.5)cm H_2O in the control group(F=6.68,P0.05).In the 4 week after the occlusion,P_(max) was(19.2±1.4)cm H_2O in the occlusion group,while(16.6±1.2)cm H_2O in the control group (F=12.10,P0.01).EEV was(86±8)ml in the occlusion group,and(96±4)ml in the control group(F=5.72,P0.05).In the occlusion group,P_(max)in the 1 week and 4 week after occlusion were higher than those at post-emphysema(P0.01,respectively);EEV at post-emphysema was higher than that at ante-emphysema(P0.01).Conclusion Coil-and-glue occlusion method for lung volume reduction in rabbit emphysema model can improve the pulmonary function,which can be relatively long lasting." @default.
- W2352878682 created "2016-06-24" @default.
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- W2352878682 date "2007-01-01" @default.
- W2352878682 modified "2023-09-28" @default.
- W2352878682 title "Minimally invasive lung volume reduction treated with bronchi occlusion emphysema model" @default.
- W2352878682 hasPublicationYear "2007" @default.
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