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- W2352884176 abstract "To establish a therapeutic model of experimental atherosclerosis in quails.The quails were randomized into three groups:control group,high lipid group,high lipid + nicotinylsalicylic acid(NSA)75mg·kg~(-1)·d~(-1) group. We established model of experimental atherosclerosis in quails with high cholesterol diet. The levels of plasma total cholesterol(TC),triglyceride(TG),low density lipoprotein-cholesterol(LDL-C) and high density lipoprotein-cholesterol(HDLC) concentration,plaque incidence rate and histopathological changes of artery and heart were observed.The level of TC,TG,LDL-C and HDL-C in serum of quails of cholesterol-diet group was increased(P0.01) at the end of 6th week;plaques were formed.The level of TC,TG,LDL-C and HDL-C in serum of quails of model group was increased continuously at the end of 11th week(P0.001);histopathological changes of artery and heart were significantly aggravated,and the typical pathological manifestation of atherosclerosis was observed.The level of TC,TG,LDLCin serum of quails of the NSA group was decreased(P0.05) and level of HDL-C was increased(P0.05).The therapeutic model of experimental atherosclerosis in quails may be conveniently established." @default.
- W2352884176 created "2016-06-24" @default.
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- W2352884176 date "2005-01-01" @default.
- W2352884176 modified "2023-09-25" @default.
- W2352884176 title "Establishment of Therapeutic Model of Experimental Atherosclerosis in Quails" @default.
- W2352884176 hasPublicationYear "2005" @default.
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