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- W2352910246 abstract "Objective:To evaluate the effect of Niao-lu-qing, a compound preparation of traditional Chinese medicine, on Neisseria gonorrhoeae in vitro. Method: By inhibition test in vitro against Neisseria gonorrhoeae, observing bacteriostasis time test, and the inhibition zone test, the effect of anti-Neisseria-gonorrhoeae was detected in Niao-lu-qing, Eight-Zheng Powder and spectinomycin. Result: Niao-lu-qing, Eight-Zheng Powder and spectinomycin were compared one another. In inhibition test in vitro against Neisseria gonorrhoeae, the effect of Niao-lu-qing was the strongest. It showed remarkable inhibitory actions on Neisseria gonorrhoeae producing penicillinase (PPNG) and producing non-penicillinase (NPPNG) in vitro. The administration concentration was within 1:512 (160 mg/L) and 1:1024 (820 mg/L) in which it could inhibit the growth of Neisseria gonorrhoeae. In bacteriostasis time test, Niao-lu-qing in high dose could quickly kill gonorrhoeae. When the concentration was in 7.81 mg/ml, Neisseria gonorrhoeae could be killed after 30 min. When the concentration was in 15.63 mg/ml, Neisseria gonorrhoeae could be killed after 20 min. When the concentration was in 31.25 mg/ml, Neisseria gonorrhoeae could be killed after 10 min. When the concentration was in 62.5 mg/ml, Neisseria gonorrhoeae could be killed after 5min. In the inhibition zone test, the average inhibition zone of Niao-lu-qing against Neisseria gonorrhoeae was within 15 to 21 mm, and the sensitive strain was 63.63%. The average inhibition zone of Eight-Zheng Powder was within 12 to 15 mm, and the sensitive strain was 54.55%. The average inhibition zone of Spectinomycin was within 16 to 19 mm, and the sensitive strain was 72.72%. Conclusion: Niao-lu-qing has good and reliable effect on anti-Neisseria gonorrhoeae in vitro." @default.
- W2352910246 created "2016-06-24" @default.
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- W2352910246 date "2010-01-01" @default.
- W2352910246 modified "2023-09-25" @default.
- W2352910246 title "Research of Niao-lu-qing on Anti-Neisseria-Gonorrhoeae in Vitro" @default.
- W2352910246 hasPublicationYear "2010" @default.
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