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- W2352989252 abstract "【Objective】 The study was to observe the effects of extracts of maize plumule given in different doses on mammary gland hyperplasia of rats and explore the mechanism for the treatment of mammary gland hyperplasia.【Method】 8 healthy rats were set as normal contrast groupⅠ.56 model rats were divided into 7 groups(groupⅡ-groupⅧ),and the model of mammary gland hyperplasia was made by hypodermic injection of oestradiol benzoate and progesterone.Model groups(Ⅱ-Ⅷ) were intragastrically administered with 0,1.25,2.5,5,10,20,40 mg/(kg·d) gradient doses maize plumule extracts.Then the length and diameter of nipples were measured,and the sex hormone of all groups checked.And the slides of mammary glands were observed by microscopic examination.【Result】 After drugs interference,medium-dose groups and high-dose groups(Ⅴ-Ⅷ) showed the mend of the mammary glands shapes and pathological tissue in vivo(P0.01));Extracts of maize plumule remarkably depressed the level of FSH,E2 and T,and raised the level of PRL and LH(P0.01) inⅤ-Ⅷ groups,but P was steady.【Conclusion】 2.5-40 mg/(kg·d) maize plumule extracts with abundant adenine derivatives conld effectively prevent and treat hyperplasia of mammary gland." @default.
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- W2352989252 date "2009-01-01" @default.
- W2352989252 modified "2023-09-25" @default.
- W2352989252 title "Effect of extracts of maize plumule on mammary gland hyperplasia rats" @default.
- W2352989252 hasPublicationYear "2009" @default.
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