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- W2353009141 abstract "ObjectiveTo observe the expressive characteristics of proliferating cell nuclear antigen(PCNA) and apoptosis,and investigate the activity of cell proliferation and apoptosis in the mouse kidney cortex during postnatal development.MethodThe expression of PCNA and apoptosis were examined in the mouse kidney cortex after birth 1,3,7,14,21,28 and 70 days by immunohistochemical technique and Tdt-mediated dUTP nick end labelling(TUNEL).Results(1) After birth,the activity of cell proliferation was prominent.At the early stage,the PCNA-positive cells were abundant.Proliferative activity tended to decrease gradually as the renal developmental stage proceeded and eventually varnished.(2) Apoptotic cells were present too.And cell death peaked later than cell proliferation.ConclusionCell proliferation and apoptosis exist(universally) in the mouse kidney cortex during postnatal development.In the early stage,the positive rate of PCNA was high,and the positive rate of apoptosis was high later,and then the activities of them were both weak." @default.
- W2353009141 created "2016-06-24" @default.
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- W2353009141 date "2006-01-01" @default.
- W2353009141 modified "2023-09-25" @default.
- W2353009141 title "Cell proliferation and apoptosis in the mouse kidney cortex during postnatal development" @default.
- W2353009141 hasPublicationYear "2006" @default.
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