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- W2353011438 abstract "The conditions of mutant strain of Saccharomyces cerevisiae YF producing glutathione in 5 L fermentor was studied. Two-level factorials designs of Plackett-Burman by Design Expert software were used to analysis fermentation conditions. Three important factors were screened, which were stirring speed, ventilation volume and pH. The experimental design and results of the three major factors were studied by response surface analysis of the central composite principle. The results showed that: the optimal value of each factor were stirring speed 187 r/min, ventilation volume 246 L/h, pH 6.36. After three parallel batches cultivation,the results showed the yield of an average of 150.27 mg/L, which is only 1.14% relative error to the predictive value. At the same time, the production output increased 75.86% than shake flask." @default.
- W2353011438 created "2016-06-24" @default.
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- W2353011438 date "2010-01-01" @default.
- W2353011438 modified "2023-09-23" @default.
- W2353011438 title "Optimization Saccharomyces cerevisiae YF fermentation conditions for glutathione producing by response surface analysis" @default.
- W2353011438 hasPublicationYear "2010" @default.
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