Matches in SemOpenAlex for { <https://semopenalex.org/work/W2353014749> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2353014749 abstract "Objective:To investigate the function of candidate tumor suppressor gene NDRG2 on proliferation and apoptosis of human esophageal cancer cell line Eca-109.Methods:Eca-109 cells were transfected with adenovirus vector containing NDRG2 gene. The expression of message RNA and protein of NDRG2 were detected by RT-PCR and Western blot respectively. The cell growth curve was drawn by methyl thiazolyl tetrazolium assay(MTT). Flow cytometry (FCM) was adopted to analyze quantitatively the cell cycle and apoptosis.Results:NDRG2 expression was significantly increased in both mRNA and protein levels in Eca-109 after transfecting with adenovirus vector carrying NDRG2 gene. As compared with normal Eca-109 cells, the growth was markedly slowed down in NDRG2 over expressing cells. The G2 phase cells were decreased significantly (P0.01), whereas S phase cells were obviously increased. Moreover, apoptotic cells which presenting typical morphologic changes of cell apoptosis, reached 16% after adenovirus transfection.Conclusion:NDRG2 gene can significantly inhibit cell growth and markedly induce the apoptosis of Eca-109 cells in vitro." @default.
- W2353014749 created "2016-06-24" @default.
- W2353014749 creator A5084357635 @default.
- W2353014749 date "2010-01-01" @default.
- W2353014749 modified "2023-09-26" @default.
- W2353014749 title "Influence of NDRG2 on proliferation and apoptosis of human esophageal cell line Eca-109" @default.
- W2353014749 hasPublicationYear "2010" @default.
- W2353014749 type Work @default.
- W2353014749 sameAs 2353014749 @default.
- W2353014749 citedByCount "0" @default.
- W2353014749 crossrefType "journal-article" @default.
- W2353014749 hasAuthorship W2353014749A5084357635 @default.
- W2353014749 hasConcept C104317684 @default.
- W2353014749 hasConcept C1491633281 @default.
- W2353014749 hasConcept C153911025 @default.
- W2353014749 hasConcept C185592680 @default.
- W2353014749 hasConcept C190283241 @default.
- W2353014749 hasConcept C2776415932 @default.
- W2353014749 hasConcept C29537977 @default.
- W2353014749 hasConcept C502942594 @default.
- W2353014749 hasConcept C54009773 @default.
- W2353014749 hasConcept C54355233 @default.
- W2353014749 hasConcept C553184892 @default.
- W2353014749 hasConcept C55493867 @default.
- W2353014749 hasConcept C62112901 @default.
- W2353014749 hasConcept C81885089 @default.
- W2353014749 hasConcept C86803240 @default.
- W2353014749 hasConcept C95444343 @default.
- W2353014749 hasConceptScore W2353014749C104317684 @default.
- W2353014749 hasConceptScore W2353014749C1491633281 @default.
- W2353014749 hasConceptScore W2353014749C153911025 @default.
- W2353014749 hasConceptScore W2353014749C185592680 @default.
- W2353014749 hasConceptScore W2353014749C190283241 @default.
- W2353014749 hasConceptScore W2353014749C2776415932 @default.
- W2353014749 hasConceptScore W2353014749C29537977 @default.
- W2353014749 hasConceptScore W2353014749C502942594 @default.
- W2353014749 hasConceptScore W2353014749C54009773 @default.
- W2353014749 hasConceptScore W2353014749C54355233 @default.
- W2353014749 hasConceptScore W2353014749C553184892 @default.
- W2353014749 hasConceptScore W2353014749C55493867 @default.
- W2353014749 hasConceptScore W2353014749C62112901 @default.
- W2353014749 hasConceptScore W2353014749C81885089 @default.
- W2353014749 hasConceptScore W2353014749C86803240 @default.
- W2353014749 hasConceptScore W2353014749C95444343 @default.
- W2353014749 hasLocation W23530147491 @default.
- W2353014749 hasOpenAccess W2353014749 @default.
- W2353014749 hasPrimaryLocation W23530147491 @default.
- W2353014749 hasRelatedWork W2352428587 @default.
- W2353014749 hasRelatedWork W2364546322 @default.
- W2353014749 hasRelatedWork W2419454767 @default.
- W2353014749 hasRelatedWork W2750728167 @default.
- W2353014749 hasRelatedWork W2905368689 @default.
- W2353014749 hasRelatedWork W3013117029 @default.
- W2353014749 hasRelatedWork W3028865066 @default.
- W2353014749 hasRelatedWork W3028889499 @default.
- W2353014749 hasRelatedWork W3029039291 @default.
- W2353014749 hasRelatedWork W3029404404 @default.
- W2353014749 hasRelatedWork W3030908309 @default.
- W2353014749 hasRelatedWork W3031256895 @default.
- W2353014749 hasRelatedWork W3031387861 @default.
- W2353014749 hasRelatedWork W3032020431 @default.
- W2353014749 hasRelatedWork W3032114459 @default.
- W2353014749 hasRelatedWork W3032358212 @default.
- W2353014749 hasRelatedWork W3032362959 @default.
- W2353014749 hasRelatedWork W3032752645 @default.
- W2353014749 hasRelatedWork W3110424444 @default.
- W2353014749 hasRelatedWork W805298610 @default.
- W2353014749 isParatext "false" @default.
- W2353014749 isRetracted "false" @default.
- W2353014749 magId "2353014749" @default.
- W2353014749 workType "article" @default.