FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2353102965> ?p ?o ?g. }

• W2353102965 endingPage "545" @default.
• W2353102965 startingPage "542" @default.
• W2353102965 abstract "Objective To clarify whether functionally competent dendritic cells (DC) can be generated from malignant pleural effusion in patients with lung cancer. Methods Malignant effusion-associated monocytes were separated by adherence from malignant effusion-associated mononuclear cells and cultured in medium with granulocyte macrophage colony-stimulating factor (GM-CSF) plus interleukin 4 (IL-4). TNF-alpha was added for the last 24 h before culture termination. Cultured DC were identified by (1) using microscopy, scanning electron microscopy, and immunocytochemistry for the morphological features; (2) phenotypic markers; and (3) functional characteristics including a high stimulatory capacity to activate proliferation of lymphocyte in an allogeneic mixed leukocyte reaction and the ability to produce high levels of IFN-gamma. Results Cultured DC had the typical morphological features. The phenotype of DCs generated from effusion showed higher expression of CD(86) (84.6 +/- 6.1)%, HLA-DR (81.1 +/- 13.0)%, CD(40) (42.0 +/- 21.7)%, CD(1a) (20.0 +/- 9.5)% and lower expression of CD(14) (4.8 +/- 3.5)% than the control group. There was a significant difference in the stimulatory activity in allogeneic lymphocyte proliferation and the ability to produce high levels of IFN-gamma between DC derived from the malignant effusion and the control group. Conclusion These findings suggest that DC can be generated from malignant pleural effusion, which might be a useful source of DC for immunotherapy." @default.
• W2353102965 created "2016-06-24" @default.
• W2353102965 creator A5004354888 @default.
• W2353102965 creator A5008206344 @default.
• W2353102965 creator A5009523738 @default.
• W2353102965 creator A5021139793 @default.
• W2353102965 creator A5028062430 @default.
• W2353102965 creator A5041738887 @default.
• W2353102965 creator A5083159278 @default.
• W2353102965 date "2004-08-01" @default.
• W2353102965 modified "2023-09-22" @default.
• W2353102965 title "Efficient generation and functional characteristics of dendritic cells from malignant pleural effusion in patients with lung cancer" @default.
• W2353102965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15388004" @default.
• W2353102965 hasPublicationYear "2004" @default.
• W2353102965 type Work @default.
• W2353102965 sameAs 2353102965 @default.
• W2353102965 citedByCount "0" @default.
• W2353102965 crossrefType "journal-article" @default.
• W2353102965 hasAuthorship W2353102965A5004354888 @default.
• W2353102965 hasAuthorship W2353102965A5008206344 @default.
• W2353102965 hasAuthorship W2353102965A5009523738 @default.
• W2353102965 hasAuthorship W2353102965A5021139793 @default.
• W2353102965 hasAuthorship W2353102965A5028062430 @default.
• W2353102965 hasAuthorship W2353102965A5041738887 @default.
• W2353102965 hasAuthorship W2353102965A5083159278 @default.
• W2353102965 hasConcept C121608353 @default.
• W2353102965 hasConcept C126322002 @default.
• W2353102965 hasConcept C137061746 @default.
• W2353102965 hasConcept C141071460 @default.
• W2353102965 hasConcept C142724271 @default.
• W2353102965 hasConcept C147483822 @default.
• W2353102965 hasConcept C163430725 @default.
• W2353102965 hasConcept C202751555 @default.
• W2353102965 hasConcept C203014093 @default.
• W2353102965 hasConcept C2776090121 @default.
• W2353102965 hasConcept C2776232967 @default.
• W2353102965 hasConcept C2776256026 @default.
• W2353102965 hasConcept C2777701055 @default.
• W2353102965 hasConcept C2777761686 @default.
• W2353102965 hasConcept C2778170410 @default.
• W2353102965 hasConcept C2778740727 @default.
• W2353102965 hasConcept C2779634585 @default.
• W2353102965 hasConcept C35866371 @default.
• W2353102965 hasConcept C502942594 @default.
• W2353102965 hasConcept C55493867 @default.
• W2353102965 hasConcept C71924100 @default.
• W2353102965 hasConcept C86803240 @default.
• W2353102965 hasConcept C8891405 @default.
• W2353102965 hasConceptScore W2353102965C121608353 @default.
• W2353102965 hasConceptScore W2353102965C126322002 @default.
• W2353102965 hasConceptScore W2353102965C137061746 @default.
• W2353102965 hasConceptScore W2353102965C141071460 @default.
• W2353102965 hasConceptScore W2353102965C142724271 @default.
• W2353102965 hasConceptScore W2353102965C147483822 @default.
• W2353102965 hasConceptScore W2353102965C163430725 @default.
• W2353102965 hasConceptScore W2353102965C202751555 @default.
• W2353102965 hasConceptScore W2353102965C203014093 @default.
• W2353102965 hasConceptScore W2353102965C2776090121 @default.
• W2353102965 hasConceptScore W2353102965C2776232967 @default.
• W2353102965 hasConceptScore W2353102965C2776256026 @default.
• W2353102965 hasConceptScore W2353102965C2777701055 @default.
• W2353102965 hasConceptScore W2353102965C2777761686 @default.
• W2353102965 hasConceptScore W2353102965C2778170410 @default.
• W2353102965 hasConceptScore W2353102965C2778740727 @default.
• W2353102965 hasConceptScore W2353102965C2779634585 @default.
• W2353102965 hasConceptScore W2353102965C35866371 @default.
• W2353102965 hasConceptScore W2353102965C502942594 @default.
• W2353102965 hasConceptScore W2353102965C55493867 @default.
• W2353102965 hasConceptScore W2353102965C71924100 @default.
• W2353102965 hasConceptScore W2353102965C86803240 @default.
• W2353102965 hasConceptScore W2353102965C8891405 @default.
• W2353102965 hasIssue "8" @default.
• W2353102965 hasLocation W23531029651 @default.
• W2353102965 hasLocation W23531029652 @default.
• W2353102965 hasOpenAccess W2353102965 @default.
• W2353102965 hasPrimaryLocation W23531029651 @default.
• W2353102965 hasRelatedWork W1585754595 @default.
• W2353102965 hasRelatedWork W1977911713 @default.
• W2353102965 hasRelatedWork W2021247456 @default.
• W2353102965 hasRelatedWork W2025551910 @default.
• W2353102965 hasRelatedWork W2028411987 @default.
• W2353102965 hasRelatedWork W2033973924 @default.
• W2353102965 hasRelatedWork W2050047423 @default.
• W2353102965 hasRelatedWork W2062580644 @default.
• W2353102965 hasRelatedWork W2075213589 @default.
• W2353102965 hasRelatedWork W2096186408 @default.
• W2353102965 hasRelatedWork W2101969344 @default.
• W2353102965 hasRelatedWork W2104041247 @default.
• W2353102965 hasRelatedWork W2161691060 @default.
• W2353102965 hasRelatedWork W2169595757 @default.
• W2353102965 hasRelatedWork W2466829444 @default.
• W2353102965 hasRelatedWork W2576240842 @default.
• W2353102965 hasRelatedWork W2803903323 @default.
• W2353102965 hasRelatedWork W2977595412 @default.
• W2353102965 hasRelatedWork W3108407483 @default.
• W2353102965 hasRelatedWork W880640307 @default.
• W2353102965 hasVolume "27" @default.
• W2353102965 isParatext "false" @default.

• next