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- W2353114328 abstract "Objective To determine whether bovine trabecular meshwork have the expression of sex hormone receptors(androgen receptor, AR; estrogen receptor alpha,ERα; and progesterone receptor, PR).Methods Newborn bovine trabecular meshwork cells were cultured in vitro and were passaged to generate the third passage. Reverse transcriptase-polymerase chain reaction(RT-PCR) was applied to determine the existence of sex hormone receptor mRNAs(AR, ERα and PR) in bovine trabecular meshwork cells. Immunohistochemical technique was used to localize these receptors in bovine trabecular meshwork cell.Results cultured cells showed the specific characteristics of bovine trabecular meshwork cells.mRNAs encoding all these receptors were found in bovine trabecular meshwork cells. Immunohistochemical examination revealed that the imimunostain of trabecular meshwork cells was positive.Conclusion Bovine trabecular cells have the expression of sex hormone receptors, which may have important role in aqueous outflow and the development of glaucoma." @default.
- W2353114328 created "2016-06-24" @default.
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- W2353114328 date "2005-01-01" @default.
- W2353114328 modified "2023-09-23" @default.
- W2353114328 title "Expression of sex hormone receptors in bovine trabecular meshwork" @default.
- W2353114328 hasPublicationYear "2005" @default.
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