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- W2353133095 abstract "Object To assess the influence of the CD14 C(-260)T promoter polymorphism located in the promoter region of the CD14 gene on C-reactive protein levels in patients with coronary artery disease.Methods Highsensitivity C-reactive protein(hs-CRP) was used as a measurement of systemic inflammation in Eighty-two patients with stable coronary artery disease.Results The genotype distribution of the C260T polymorphism of the CD14 gene was as follows:CC in 18 of 82 patients(22%),TC in 48 of 82 patients(58.5%),and TT in 16 of 82 patients(19.5%).TT subjects had increased hs-CRP levels compared with carriers of the C allele(P=0.04).A higher percentage of T allele homozygotes had hs-CRP levels0.3mg/dl(P=0.01).Conclusions T homozygotes of this functional polymorphism are at increased ischemic risk,and it is independently associated with hs-CRP levels0.3mg/dl(P=0.004)." @default.
- W2353133095 created "2016-06-24" @default.
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- W2353133095 date "2007-01-01" @default.
- W2353133095 modified "2023-09-27" @default.
- W2353133095 title "Influence of the CD14 C(-260)T promoter polymorphism on C-reactive protein levels in patients with coronary artery disease" @default.
- W2353133095 hasPublicationYear "2007" @default.
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