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- W2353187600 abstract "Objective To investigate the change of distribution of c-fos and neuropetides in the lung of asthmatic rat.Methods Thirty-two Wistar rats were divided into control group,asthmatic recover group,acute episode group,dexameth intervention group.Immunohistochemistry and computer image analysis were used to observe the c-fos change of the lung and the contents of substance P(SP)and vasoactive intestinal peptide(VIP)in lung tissues were detected by ELISA.Results The contents of SP in the BALF of asthmatic recover group,acute episode group,dexameth intervention group rats were significantly higher than that in control group(P0.000 1),and the contents of VIP were significantly lower.There were significantly positive correlations between the SP and the optical density value of c-fos(r=0.908,0.967,0.865,P0.05or 0.001).There were significantly negative correlations between VIP and optical density value of c-fos(r=-0.974,-0.949,-0.962,Pall≤0.001).Conclusion There is correlation between neuropeptides,c-fos proteinum and asthmatic attack asthmatic rats." @default.
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- W2353187600 date "2014-01-01" @default.
- W2353187600 modified "2023-09-23" @default.
- W2353187600 title "Correlation of distribution of c-fos and neuropetdides in lung of asthmatic rat" @default.
- W2353187600 hasPublicationYear "2014" @default.
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