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- W2353200896 abstract "Objective:To observe the influence of the heat-asthma prescription on the airway inflammation and remodeling of asthmatic rats and investigate the mechanism of heat-asthma prescription.Methods:40 Wistar rats were selected and divided into 5 groups in the experiment:normal group,model group,heat-asthma prescription group,budesonide group,heat-asthma prescription combined with budesonide group.The effect of different experiment drugs on IL-4,INF-γ,NE,MMP-9,TIMP-1,and the pathomorphological changes of the lung of the rats were recorded.Results:The contents of IL-4,INF-γ,NE,MMP-9,TIMP-1 and the TIMP-1/MMP-9;the thickness of the airway mucosa and smooth muscle directly;the infiltration of the airway inflammatory cell were improved in all groups except normal and model group.Further more,the heat-asthma prescription combined with budesonide group was better than heat-asthma prescription group and budesonide group.Conclusion:The heat-asthma prescription can reduce airway inflammation,inhibit and improve airway remodeling.The combination of heat-asthma prescription and budesonide can take the best effect." @default.
- W2353200896 created "2016-06-24" @default.
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- W2353200896 date "2010-01-01" @default.
- W2353200896 modified "2023-09-22" @default.
- W2353200896 title "Influence of the Heat-asthma Prescription on the Airway Inflammation and Remodeling of Asthmatic Rats" @default.
- W2353200896 hasPublicationYear "2010" @default.
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