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- W2353205870 abstract "Objective:To compare the effect of direct percutaneous transluminal coronary angioplasty (PTCA)and Urokinase (UK) thrombolytic therapy in acute myocardial infarction(AMI). Methods:This is an observing cohort study. 97 cases of AMI were treated by emergency PTCA while 60 cases of AMI were treated by thrombolytic therapy with UK. We then compared the results of echocardiogrophic examination (UCG) and clinical effects both in hospital and the follow-up period. Results:In hospital period , the UCG examination showed that the percentage of patients with normal wall motion was higher in PTCA group (46.00%) than that in UK group(24.73%)(p=0.021).The rates of dyskinesia was 11.83% in thrombolytic group and higher than that in PTCA (0) .The left ventricular ejection fraction (LVEF %) in PTCA group ( 56.88±10.47) was higher than that in UK group(51.58±10.97)(p=0.041)?During hospital , the rates of heart failure in PTCA group (18.33%) was less than that in UK group (32.59%) (p=0.029). The accumulative heart failure rate during follow-up period in PTCA group (5.19%) was also less than that in UK group(16.28%)(p=0.001). The mortality during hospital in PTCA group was less than that in UK group, but showed no significant difference. The accumulative mortality was 5.00% in PTCA group and less than that in UK group (15.56%) (p=0.021). The accumulative mortality of patients over 60 years of age in PTCA group(10.34%)was also less than that in UK group(28.99%)(p=0.049)?During follow-up, the scores of life quality in patients of PTCA group were higher than those in the UK group. Conclusion:direct PTCA therapy limited left ventricular re-modeling, improves the heart function and quality of life , decreases the rate of heart failure and mortality." @default.
- W2353205870 created "2016-06-24" @default.
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- W2353205870 date "2002-01-01" @default.
- W2353205870 modified "2023-09-25" @default.
- W2353205870 title "A comparison of direct angioplasty with Urokinase thrombolytic therapy for acute myocardial infarction" @default.
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