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- W2353207030 abstract "Objective To investigate the changes of Interleukin-10(IL-10),and C-reactive protein(CRP)levels in patients with acute exacerbation of chronic obstructive pulmonary diseases(AECOPD)and to analyze the correlation between the inflammatory factor and COPD.Methods The levels of IL-10 and CRP in thirty cases of patients with AECOPD were measured by enzyme-linked immunosorbcot assay.The amounts of neutmphils,PaO 2 and lung function indexes such as the forced expiratory volume in one second(FEVl)and the forced expiratory volume in one second/forced vital capacity(FEVl/FVC)were also determined.Results From the time of beginning therapy to the time of after-therapy,the AECOPD patients showed a significant decrease in IL-10[(176.5±71.0)pg/L,(219.9±105.2)pg/L respectively)vs(359.3±156.1)pg/L],but showed a notable increase in CRP[(23.9±17.8)mg/L,(10.1±4.2)mg/L respectivdy)vs(6.7±1.8)mg/L].serum IL-10 concentrations with FEV1%(P0.05) and FEV1/FVC(P0.05) were positively correlated,while CRP with FEVl%(P0.05) and FEVl/FVC(P0.05) were negatively correlated.Conclusion The serum IL-10 levels in the patients with AECOPD is lower than that of the healthy control group,While IL-10 and CRP levels are higher than that of the healthy control group.The damage of lung function in patients with AECOPD is associated with the serum levels of IL-l0 and CRP." @default.
- W2353207030 created "2016-06-24" @default.
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- W2353207030 date "2009-01-01" @default.
- W2353207030 modified "2023-09-23" @default.
- W2353207030 title "Study of Function of CRF、IL-10 in Acute Exacerbation of COPD" @default.
- W2353207030 hasPublicationYear "2009" @default.
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