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- W2353283962 abstract "Objective To study the effect of hydroxyl camptothecinum on human lung cancer cell apoptosis in vitro.Methods SPC A 1 cell line was treated with hydroxyl camptothecinum at different concentrations.Cell apoptosis was evaluated by electron microscopy,flow cytometry,and in situ TUNEL (TdT mediated dUTP X nick end labeling).Results The apoptosis rate of lung cancer cell treated with hydroxyl camptothecinum at the concentration of 0.05 mg/ml for 20 hours was between 8.7 % 10.4 %,mainly at early and middle apoptosis stage.At the concentration of 0.1 mg/ml,the rate was 18.6 %,mainly at late stage.Conclusion Hydroxyl camptothecinum is a potential agent for lung cancer chemotherapy.$$$$" @default.
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- W2353283962 date "2000-01-01" @default.
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- W2353283962 title "INDUCTION OF APOPTOSIS IN HUMAN LUNG CANCER CELL LINE SPC A 1 BY HYDROXYL CAMPTOTHECINUM" @default.
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