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- W2353312338 abstract "Objective:To explore the clinical efficacy and safety of ziprasidone in the treatment of first-episode schizophrenia.Methods:72 fitst-episode schizophrenis were randomly divided into reaearch group(n=36)took orally ziprasidone and contral group(n=36)doing chlorpromazine for 8 weeks.clinical efficacies were assessed with the positive and Negative Syndrome Scale(PANSS) and adverse reactions with the Treatment Emergent Symptom Scal(TESS).before treatment and at the end of the 1st,2nd,4th and 8th week.Results: At the end of the 8th week,total effective rates were 88.9% in the research and 88.1% in the control group respectively(P0.05);the total and all factor scores of the PANSS of both groups lowered more significantly compared with pretreatment(P0.05or0.01);scores of negative symptoms lowere more significantly in the research than in the control group(P0.05);EPS rate of adverse reaction was significantly lower in the research than in the control group(P0.05).Conclusions: Ziprasidone has evident effect equivalent to chlorpromazine,improves the negative symptoms more significantly and has lower EPS rale of adverse reaction,take efects faster,and has highter safety and better compliance." @default.
- W2353312338 created "2016-06-24" @default.
- W2353312338 creator A5015185874 @default.
- W2353312338 date "2012-01-01" @default.
- W2353312338 modified "2023-09-24" @default.
- W2353312338 title "A control study of ziprasidone vs.chlorpromazine in the treatment of first-episode schizophrenia" @default.
- W2353312338 hasPublicationYear "2012" @default.
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