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- W2353331464 abstract "Objective The purpose of the study was to observe if restoration of spontaneous circulation (ROSC) was enhanced after delayed administration of vasopressin and epinephrine in cardiopulmonary resuscitation (CPR) and to compare the effectiveness of two drugs in asphyxial rabbit models of CPR. Methods At 8 minutes after the endotracheal tube had been clamped, cardiac arrest (CA) was present in 62 rabbits, then received CPR. During five-minute CPR, animals which had ROSC were defined as successfully resuscitated rabbits,but those which had not ROSC were randomly divided into two groups to receive vasopressin (0.8 IU/kg) or epinephrine (0.2 mg/kg). Results The ROSC of routine CPR (without any drugs) was 24.19% (15/62) within five minutes, and total ROSC reached 48.39% (30/62) after epinephrine and vasopressin administration. ROSC was significantly higher in the epinephrine group, compared with the vasopressin group (13/24 vs. 2/23, P=0.001). Conclusion The rate of ROSC increased after epinephrine and vasopressin administration. Epinephrine is more effective than vasopressin in asphyxial rabbit models of CPR." @default.
- W2353331464 created "2016-06-24" @default.
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- W2353331464 date "2005-01-01" @default.
- W2353331464 modified "2023-09-23" @default.
- W2353331464 title "Comparison of delayed administration of vasopressin and epinephrine in asphyxial rabbit models of cardiopulmonary resuscitation" @default.
- W2353331464 hasPublicationYear "2005" @default.
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