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- W2353375420 abstract "Toll-like receptors (TLRs) is a family of pattern recognizing receptors closely related to nature immune.PAMP is the molecular marker expressed on the cell surface with pathogen infection,which tends to be conservative during evolution and can be recognized by TLR.TLR2 and TLR4 play the leading role in the family of TLRs,The receptor for LPS is TLR4,and TLR2 is the main receptor of LTA.Both of them can result in the releasing of inflammatory factors by inducing the cellular signal transduction system,which play an important role in natural immune as well as the following adaptive immunity.The genetic polymorphism of TLRs is associated with individual susceptibility to diseases.TLR play an important role in recognizing pathogen and initiating inflammatory response.The studies of TLRs and activated processes during natural immune will have frther influence on the development and recognition and then provide important refernence for the diagnosis and treatment of diseases." @default.
- W2353375420 created "2016-06-24" @default.
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- W2353375420 date "2008-01-01" @default.
- W2353375420 modified "2023-09-26" @default.
- W2353375420 title "Progress of the Study on Toll-like Receptors" @default.
- W2353375420 hasPublicationYear "2008" @default.
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