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- W2353393756 abstract "Objective: Four green and red fluorescent protein transferred human breast cancer models were established, to research on the combined effect of Bolbostemma Paniculatum Saponins and Peimine in vitro of four human breast cancer cells. Methods: By transfection and filtering, four green and red fluorescent protein transferred human breast cancer models were established, including MDA-MB-231 DUAL, BT-549 DUAL, MCF-7 DUAL, and NCI/ADR-RES DUAL(the cytoplasm express RFP, and the nucleus express GFP). The morphological change and apoptosis of the cell models on the cooperation effect of Bolbostemma Paniculatum Saponins and Peimine were observed with inverted real-time fluorescence microscopy imaging. Results: The Bolbostemma Paniculatum attract could enhance the apoptosis of the four human breast cancer cell models. The same concentration of Bolbostemma Paniculatum attracts combined with the application of Peimine could improve the apoptosis rate of human breast cancer cells(P0.05), except MDA-MB-231 DUAL cell. However, Peimine alone had no significant impact on four human breast cancer cell models. Conclusion: The combination of Bolbostemma Paniculatum Saponins and Peimine could promote the apoptosis of human breast cancer cell, and improve the efficacy. The higher the concentration of Bolbostemma Paniculatum Saponins and Peimine, the more significant the apoptosis rate is." @default.
- W2353393756 created "2016-06-24" @default.
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- W2353393756 date "2015-01-01" @default.
- W2353393756 modified "2023-09-25" @default.
- W2353393756 title "Study on the combined function of Bolbostemma Paniculatum Saponins and Peimine in vitro of human breast cancer cell" @default.
- W2353393756 hasPublicationYear "2015" @default.
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