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- W2353411417 abstract "Objective:To investigate the expression of surviving in gallbladder carcinoma and its relationship with clinical and pathological condition.Methods:In tissue of gallbladder carcinoma and paracarcinoma and chronic inflammational gallbladder,the expression of survivin mRNA was detected by RT-PCR technique,the expression of survivin protein was detected by immunohistological methods.Their clinical and pathological condition was analyzed.Results:In 28 cases of gallbladder carcinoma,the positive rate of expression of survivin gene was 71.4%,which was similar to the result of immunohistological examination.In 22 cases of paracarcinoma and chronic inflammational gallbladder,the expression of survivin protein was negative.The positive rate of survivin in gallbladder in stage of Ⅳ and Ⅴ was respectively 88.0%and 100%,higher than that in stage of Ⅰ(32.6%),Ⅱ(59.9%)and Ⅲ(66.8%)(P0.05).The level of expression of survivin showed difference in gallbladder in different differentiation(P0.05),but the expression,but the rate of that showed no difference(P0.05).Conclusion:The expression of survivin protein and its Mrna in primary gallbladder is upregulated.The results by two methods is similar." @default.
- W2353411417 created "2016-06-24" @default.
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- W2353411417 date "2008-01-01" @default.
- W2353411417 modified "2023-09-23" @default.
- W2353411417 title "The Expression of Survivin In Primary Gallbladder Carcinoma and Its Significance" @default.
- W2353411417 hasPublicationYear "2008" @default.
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