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- W2353437388 abstract "Objective:To study the effects of doxifluridine(DFUR) lyophilized powder for injection(DFURLP) on the experimental tumors:S 180 ,Heps and U 14 in mice.Methods:The activity of DFUR(300,150,75mg·kg -1 ) was observed to measure the survival time of mice with the three ascitic type and the weight of the tumor.Results:The growth of S 180 ,Heps and U 14 in mice was significantly( P 0.01) inhibited by DFURLP.The effects of DFURLP (300mg·kg -1 ) following iv administration was similar to those of DFUR (600mg·kg -1 ) following ig administration. DFURLP(300,150 mg· kg -1 ) following ip administration could significantly prolong the survival time of mice with S 180 ,Heps of ascitic type and EAC,but DFUR (300mg·kg -1 ) following ig administration could not significantly prolong the survival time of mice with the three ascitic type.Conclusion:The experimental tumors(S 180 ,Heps,and U 14 ) in mice were significantly inhibited by DFURLP following iv or ip administration." @default.
- W2353437388 created "2016-06-24" @default.
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- W2353437388 date "2002-01-01" @default.
- W2353437388 modified "2023-09-22" @default.
- W2353437388 title "The study of the antitumor effect of doxifluridine lyophilized powder for injection" @default.
- W2353437388 hasPublicationYear "2002" @default.
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