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- W2353583239 abstract "Objective:To observe the effects of Zedan Infusion on Smad3 and TGF-β1in the rats with Chronic pelvic inflammatory disease,so as to discuss its mechanism.Methods:The rat model of chronic pelvic inflammatory disease was established by injecting coli suspension(concentration of about 6×106)0.2ml to the bilateral intrauterine.After the modeling,the rats were randomly divided into Zedan Infusion high and medium(8g·kg,4g·kg)dose group,Fule particle group(2.5g·kg),model group and the normal group.After oral administration 21 d,the expression of TGF-β1and Smad3 was assayed by the Western Blot.Results :Compared with the model group,the expression of TGF-β1and Smad3 was significantly lower(P0.05),which was better in Zedan infusion high and medium dose group than in Fule group(P0.05).Conclusion:Zedan infusion can reduce the abnormal expressions of TGF-β1and Smad3,has anti-tissue adhesions and fibrosis effects,thus it has good clinical efficacy on Chronic pelvic inflammatory disease." @default.
- W2353583239 created "2016-06-24" @default.
- W2353583239 creator A5073422159 @default.
- W2353583239 date "2015-01-01" @default.
- W2353583239 modified "2023-09-26" @default.
- W2353583239 title "Effects of Zedan infusion on Smad3 and TGF-β1 in rats with chronic pelvic inflammatory disease" @default.
- W2353583239 hasPublicationYear "2015" @default.
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