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- W2353685983 abstract "Objective It has been reported that the hypothalamic GnRH affects the activation of thymic lymphocytes as an immune modulator. However, whether thymus itself produces GnRH is not completely clear. Thus, the existence of GnRH and the expression of GnRH|mRNA in rat thymus were studied in this article.Methods The immunohistochemistry and in situ hybridization were used in the present study. Results There was hypothalamic GnRH like substance expression in rat thymus at both the polypeptide and the mRNA. The GnRH|mRNA was not only expressed in thymic epithelial cells, but also in part of the lymphocytes and macrophages of cortex and medulla. Conclusion This result indicated that GnRH might be a bidirectional factor between immune system and neuroendocrine system." @default.
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- W2353685983 date "2000-01-01" @default.
- W2353685983 modified "2023-09-25" @default.
- W2353685983 title "THE EXPRESSION OF GnRH-mRNA IN RAT THYMUS" @default.
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