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- W2353703722 abstract "Objective To find out the influence of patients with HBV infection and transfusion-transmitted virus (TTV) co-infection on their clinical outcome and the replication of HBV infection. Methods TTV-DNA was test by Microplate Sandwich Hybridization-ELISA technique and markers of HBV was test by ELISA in 152 patients with hepatitis B virus infection, and the results and clinical data were analyzed statistcally. Results TTV-DNA was found in 23 of the 152 (15.13%) patients. Among them, 2/18(11.1%) asymptotic carriers(ASC), 8/54(14.8%) patients with chronic hepatitis B(CHB), 6/40(15.0%) patients with active liver cirrhosis(ALC), and 7/38(18.4) patients with hepatocarcinoma(HCC) were TTV DNA positive, but there was no statistical difference among the four groups of ACS、CHB、ALC and HCC. The liver function test showed no significant different between group of simple HBV infected and group of co-infection with HBV and TTV. In patients with co-infection of HBV and TTV, the positive rates of HBeAg and anti-HBcIgM in serum were lower than those in patients with simple HBV infection( p0.01 and p0.05 respectively) but the positive rate of anti-HBe was significantly higher as compared with the patients of simple HBV infection ( p0.01) . Conclusions The results showed that TTV co-infection could not affect the clinical outcome of patients, but may play the role in the inhibition of HBV replication." @default.
- W2353703722 created "2016-06-24" @default.
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- W2353703722 date "2004-01-01" @default.
- W2353703722 modified "2023-09-23" @default.
- W2353703722 title "The Study of Patients with HBV Infection and Virus of TTV Co-infection" @default.
- W2353703722 hasPublicationYear "2004" @default.
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