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- W2353769621 abstract "Objectives The aim of the present study was to investigate effects of oral prednisolone on serum concentration of interleukin-16 and monocyte chemoattractant protein-4 in patients with allergic asthma.Methods We measured the serum concentrations of interleukin-16 and monocyte chemoattractant protein-4 in 25 patients with atopic asthma before and after 2 wk of treatment with prednisolone,30 mg/d,or placebo in a randomized,double-blind,parallel group study.Results In the prednisolone-treated asthmatics,there was a significant decrease in serum concentrations of either interleukin-16 or monocyte chemoattractant protein-4 after 2 wk of glucocorticoid therapy compared with baseline values(371.5±45.5 ng/L versus 544.1±60.5 ng/L,p = 0.001;330.2±41.3 ng/L versus 455.9±48.8,P= 0.01 ng/L;respectively),whereas there were no significant differences in the placebo group.Conclusions These results suggest that short-term oral corticosteroid modulates serum concentrations both interleukin-16 and monocyte chemoattractant protein-4 in patients with allergic asthma." @default.
- W2353769621 created "2016-06-24" @default.
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- W2353769621 date "2006-01-01" @default.
- W2353769621 modified "2023-09-28" @default.
- W2353769621 title "Effects of oral glucocorticoid on serum concentrations of interleukin-16 and monocyte chemoattractant protein-4 in allergic asthmatics." @default.
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