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- W2353778961 abstract "Objective To analyze the characteristics and risk factors of clopidogrel resistance in elderly hospitalized patients combined with type 2diabetes mellitus(T2DM)and coronary heart disease(CHD).Methods A total of 315cases were divided into control group(n=196),with the platelet aggregation inhibition rate(△A)detected 24hours after taking clopidogrel more than 10%,and observation group with △A not more than 10%(n=119). Retrospectively analysis of the differences of cardiovascular disease risk factors,blood sugar,lipid metabolism and inflammation index level between the two groups were performed.Results Compared with control group,there were no significant statistically difference in sex,ages,body mass index(BMI),smoking history,incidence of hypertension and hyperlipidemia,and levels of triacylglycerol,total cholesterol,low density lipoprotein cholesterol and glycated hemoglobin in observation group(P0.05).Levels of hypersensitive C-reactive protein,fasting glucose and glycosylated serum protein were significantly higher in observation group,but level of high-density lipoprotein cholesterol was significantly lower(P0.01),compared with control group.Conclusion Clopidogrel resistance might be obvious in elderly patients combined with T2DM and CHD,and the risk factors could include increased levels of hypersensitive C-reactive protein,fasting glucose,glycosylated serum protein,and decreased level of high-density lipoprotein cholesterol." @default.
- W2353778961 created "2016-06-24" @default.
- W2353778961 creator A5051673154 @default.
- W2353778961 date "2014-01-01" @default.
- W2353778961 modified "2023-09-27" @default.
- W2353778961 title "Analysis of risk factors of clopidogrel resistance in elderly patients combined with diabetes mellitus and coronary heart disease" @default.
- W2353778961 hasPublicationYear "2014" @default.
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