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- W2353824740 abstract "Objective To investigate on free radical theory the influence of acupuncture on intracerebral injury due to free radical oxidation in simulate Alzheimer’s Disease(AD) rats. Methods A maze was used to observe the influence of acupuncture on learning and memory ability in simulate AD rats. Malonic dialdehyde(MDA) content, glutathion-peroxidase(GSH-Px) activity and superoxide dismutase(SOD) activity in rat cerebral cortex were determined by spectrophotometry before and after acupuncture. Results A test in maze learning and memory ability showed that it was significantly better in the acupuncture group of rats than in the model group(P0.01) and also in the Piracetam group(P0.05). Corticocerebral MDA content was significantly lower(P0.01) and SOD and GSH-Px activities were significant higher(P0.01) in the acupuncture group than in the model group. Three were significant differences between the acupuncture and Piracetam groups(P0.05). Conclusion Acupuncture has a reducing effect on injury to the antioxidation system by free radicals and high lipid peroxidation, suggesting that acupuncture can improve intracerebral antioxidation ability, lessen intracerebral injury to neurons by free radicals and reduce AD lesion." @default.
- W2353824740 created "2016-06-24" @default.
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- W2353824740 date "2005-01-01" @default.
- W2353824740 modified "2023-09-23" @default.
- W2353824740 title "The Influence of Acupuncture on Intracerebral Free Radical Oxidation Injury in Simulate AD Rats" @default.
- W2353824740 hasPublicationYear "2005" @default.
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