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- W2353873485 abstract "In this paper, metabolic networks of the Corynebacterium glutamicum GWY020 and the two de-rivatives carrying additional mutations HUI821and GUI089 were established and modified. The concentra-tions of extra-cellular metabolites were determined under sub-steady-state (50 h~52 h) of the batch culture. The metabolic flux distribution maps of the three strains were obtained, compared and analyzed. These re-sults indicate that the introduction of analog supersensitive marker or analog resistant marker skew the metabolic flux towards the formation of L-Arginine. This study revealed the usefulness of the metabolic flux analysis as a tool for verification of existing production strains. The analysis may play an important role in helping us to rationally re-design metabolism for further improvement of fermentation process." @default.
- W2353873485 created "2016-06-24" @default.
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- W2353873485 date "2008-01-01" @default.
- W2353873485 modified "2023-09-25" @default.
- W2353873485 title "Metabolic Flux Analysis of L-Arginine Fermentation in Corynebacterium glutamicum" @default.
- W2353873485 hasPublicationYear "2008" @default.
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