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- W2353897533 abstract "Kanamycin(KAN)as a chiral selector for the enantiomeric separation of hydrochloric dipivefrin(HD)by capillary electrophoresis(CE)was reported.The influences of the chiral selector concentration,buffer pH,capillary temperature,and the additives of organic modifier on the enantioseparation were all investigated and the separation conditions were optimized.The optimal separation conditions were as following.The concentration of KAN was 0.6%,the concentration of organic modifier was 5% and a mixture of acetonitrile and methanol(9∶1,V/V)was used as the modifier.Phosphate buffer with pH 2was used.The injection amount of HD was 25psi for 2s.The applied voltage on separation and capillary temperature were + 20kV and 25 ℃,respectively.The detection waveleagth was 262nm.The results show that capillary electrophoresis is a fast and efficient separation method for enantioseparation of chiral drugs and that KAN is a viable chiral selector in CE for the separation of HD." @default.
- W2353897533 created "2016-06-24" @default.
- W2353897533 creator A5035103923 @default.
- W2353897533 date "2013-01-01" @default.
- W2353897533 modified "2023-09-28" @default.
- W2353897533 title "Kanamycin as a New Chiral Selector in Enantiomeric Separation of Hydrochloric Dipivefrin by Capillary Electrophoresis" @default.
- W2353897533 hasPublicationYear "2013" @default.
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