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- W2353968383 abstract "Objective To observe the clinical effect and safety of Jieyu Jiaonang combined with paroxetine tablets on depression. Methods Totally 100 depression patients were randomly divided into treatment group and control group with 50 cases in each group. At last,there were respectively 49 cases accomplished the trial in both groups. Treatment group was given Jieyu Jiaonang 4 capsules each time,3 times each day and paroxetine tablets 20 mg each time,1 time each day orally,and the control group was given paroxetine tablets only,for 6 weeks. Compare Hamilton Depression Scale( HAMD),Hamilton Anxiety Scale( HAMA),Clinical Global Impression Scale( CGI)including severity of illness( SI),global improvement( GI) and efficacy index( EI),clinical effect and adverse reactions. Results After 2,4,6 weeks,total scores of HAMD,HAMA and SI in both groups decreased obviously( P 0. 01). Total scores of HAMD,GI and EI of treatment group were lower than those of control group at the same time point( P 0. 05 or P 0. 01). Total scores of HAMA and SI of treatment group were lower than that of control group at the same time point( 2nd,6th week,P 0. 05 or P 0. 01). After treatment,all factors' scores in HAMD of both groups decreased significantly at different time( P 0. 05 or P 0. 01). After 2 weeks,factors' scores of anxiety,weight,sleep disorder and despair of treatment group were lower than that of control group( P 0. 05 or P 0. 01). After 4 weeks,the factor score of feeling in morning or evening was lower than that of control group( P 0. 01). After 6 weeks,factors' scores of anxiety,cognition,retardation and despair were lower than that of control group( P 0. 05 or P 0. 01). The clinical effect of treatment group was superior to control group( P 0. 01).Conclusion Jieyu Jiaonang combined with paroxetine tablets could improve clinical effect in depression,with less adverse reactions than Western medicine alone." @default.
- W2353968383 created "2016-06-24" @default.
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- W2353968383 date "2015-01-01" @default.
- W2353968383 modified "2023-09-26" @default.
- W2353968383 title "Clinical Observation on Jieyu Jiaonang( 解郁胶囊) Combined with Paroxetine Treating 50 Depression Cases" @default.
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