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- W2353982544 endingPage "3885" @default.
- W2353982544 startingPage "3861" @default.
- W2353982544 abstract "The ability to rapidly restore the integrity of a broken skin barrier is critical and is the ultimate goal of therapies for hard-to-heal-ulcers. Unfortunately effective treatments to enhance healing and reduce scarring are still lacking. A deeper understanding of the physiology of normal repair and of the pathology of delayed healing is a prerequisite for the development of more effective therapeutic interventions. Transition from the inflammatory to the proliferative phase is a key step during healing and accumulating evidence associates a compromised transition with wound healing disorders. Thus, targeting factors that impact this phase transition may offer a rationale for therapeutic development. This review summarizes mechanisms regulating the inflammation-proliferation transition at cellular and molecular levels. We propose that identification of such mechanisms will reveal promising targets for development of more effective therapies." @default.
- W2353982544 created "2016-06-24" @default.
- W2353982544 creator A5016578378 @default.
- W2353982544 creator A5019510030 @default.
- W2353982544 creator A5048481444 @default.
- W2353982544 date "2016-05-14" @default.
- W2353982544 modified "2023-10-17" @default.
- W2353982544 title "Transition from inflammation to proliferation: a critical step during wound healing" @default.
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