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- W2354028305 abstract "Objective To investigate the expression of IGF?Ⅰ mRNA in renal carcinoma.Methods RT?PCR was used to detect IGF?Ⅰ mRNA expression in specimens from 25 renal cancers and normal tissues around the cancer. Results It was shown that IGF?Ⅰ mRNA were negative in 2,weakly positive in 13 and moderately positive in 10 among 25 renal cancers, whereas 8 were negative, 13 were weakly positive and 4 were moderately positive among 25 normal tissue around the cancer. IGF?Ⅰ mRNA expression was higher ( P 0.05) in renal cancers than that in normal tissue. Among 16 Ⅰ,Ⅱ stage cancers, 2 were negative, 11 were weakly positive, 3 were moderately positive, whereas 2 were weakly positive and 7 were moderately positive among 9 Ⅲ, Ⅳ stage carcinomas. IGF?Ⅰ mRNA expression was significantly higher ( P 0.05) in Ⅲ,Ⅳ stage cancers than that in Ⅰ,Ⅱ stage ones.Conclusion IGF?Ⅰ mRNA might enable renal cancer cells to spread." @default.
- W2354028305 created "2016-06-24" @default.
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- W2354028305 date "2001-01-01" @default.
- W2354028305 modified "2023-09-25" @default.
- W2354028305 title "IGF-ImRNA Expression in Renal Carcinomas and its Relationship with Metastasis" @default.
- W2354028305 hasPublicationYear "2001" @default.
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